Methylenetetrahydrofolate Reductase Deficiency

Causes of Methylenetetrahydrofolate Reductase Deficiency

User reported causes of Methylenetetrahydrofolate Reductase Deficiency based on their intuition.

Cause	Agree
Paternal / Maternal Stress (Smoke, Drinking, Lifestyle)	86%
Genetic Gene Mutation	61%
Compound Heterozygous C677T and A1298C	55%
Two Copies of 677TT (Homozygous)	31%
Maternal Exposure to DNA Mutation Agents	21%
C677T Single Mutation	17%
Age of Mother at Birth	15%
Two Copies of 677C (Heterozygotes)	9%

User-reported effectiveness in treating Methylenetetrahydrofolate Reductase Deficiency

Treatment	Major Improvement	Moderate Improvement	Much Worse	No Effect	Worse	Responses
Vitamin D	25%	25%	0%	50%	0%	4
Lovenox	100%	0%	0%	0%	0%	1
Folic Acid	25%	25%	25%	25%	0%	4
Prednisone	0%	100%	0%	0%	0%	1
Metanx	0%	0%	0%	100%	0%	2
5-Methyltetrahydrofolate (5-MTHF)	50%	17%	0%	33%	0%	6
L-Methylcobalamin	25%	50%	0%	25%	0%	4
B12	17%	50%	0%	33%	0%	12
L-Methylfolate	0%	100%	0%	0%	0%	1
Baby Aspirin	20%	20%	0%	60%	0%	5
Prenatal Vitamin	0%	25%	0%	75%	0%	8
B100 Complex	11%	22%	11%	56%	0%	9

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Outcomes

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% Change from Baseline*

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Predictors

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Change from the average seen after the predictor is higher than average.

Property	Value
Variable Name	Methylenetetrahydrofolate Reductase Deficiency
Aggregation Method	MEAN
Analysis Performed At	2020-03-02
Duration of Action	24 hours
Maximum Allowed Value	5 out of 5
Minimum Allowed Value	1 out of 5
Number of Aggregate Predictors	0
Number of Aggregate Outcomes	0
Number of Measurements	0
Number of Measurements (including those generated by tagged, joined, or child variables)	0
Public	true
Onset Delay	0 seconds
Unit	1 to 5 Rating
User Variables	0
Variable Category	Symptoms
Variable ID	86864